Submitted by davidmau on Thu, 01/03/2019 - 21:22
TitleTranslational Meta-analytical Methods to Localize the Regulatory Patterns of Neurological Disorders in the Human Brain.
Publication TypeJournal Article
Year of Publication2015
AuthorsSochat V, David M, Wall DP
JournalAMIA Annu Symp Proc
Volume2015
Pagination2073-82
Date Published2015
ISSN1942-597X
KeywordsBrain, Brain Mapping, Humans, Nervous System Diseases, Neuroimaging, Pattern Recognition, Automated, Phenotype
Abstract

The task of mapping neurological disorders in the human brain must be informed by multiple measurements of an individual's phenotype - neuroimaging, genomics, and behavior. We developed a novel meta-analytical approach to integrate disparate resources and generated transcriptional maps of neurological disorders in the human brain yielding a purely computational procedure to pinpoint the brain location of transcribed genes likely to be involved in either onset or maintenance of the neurological condition.
Alternate JournalAMIA Annu Symp Proc
PubMed ID26958307
PubMed Central IDPMC4765688