Title | Translational Meta-analytical Methods to Localize the Regulatory Patterns of Neurological Disorders in the Human Brain. |
Publication Type | Journal Article |
Year of Publication | 2015 |
Authors | Sochat V, David M, Wall DP |
Journal | AMIA Annu Symp Proc |
Volume | 2015 |
Pagination | 2073-82 |
Date Published | 2015 |
ISSN | 1942-597X |
Keywords | Brain, Brain Mapping, Humans, Nervous System Diseases, Neuroimaging, Pattern Recognition, Automated, Phenotype |
Abstract | The task of mapping neurological disorders in the human brain must be informed by multiple measurements of an individual's phenotype - neuroimaging, genomics, and behavior. We developed a novel meta-analytical approach to integrate disparate resources and generated transcriptional maps of neurological disorders in the human brain yielding a purely computational procedure to pinpoint the brain location of transcribed genes likely to be involved in either onset or maintenance of the neurological condition. |
Alternate Journal | AMIA Annu Symp Proc |
PubMed ID | 26958307 |
PubMed Central ID | PMC4765688 |